TB-500 (Thymosin Beta-4) is a naturally occurring 43-amino acid peptide that plays a crucial role in cellular repair, regeneration, and protection. This research-grade synthetic version of thymosin beta-4 is identical to the endogenous peptide found in high concentrations in blood platelets, wound fluid, and various tissues throughout the body. TB-500 has gained significant attention in regenerative medicine research for its remarkable ability to promote tissue healing, angiogenesis, and cellular migration.

Research Applications & Scientific Mechanisms:

🩸 Vascular & Angiogenesis Research:

Promotes endothelial cell differentiation and blood vessel formation
Enhances angiogenesis in dermal tissues and wound sites
Stimulates growth of new blood vessels from pre-existing vasculature
Improves vascular density and circulation in damaged tissues
Research applications in cardiovascular disease and tissue perfusion studies

🧬 Cellular Migration & Tissue Repair:

Facilitates keratinocyte migration for wound healing
Promotes actin polymerization and cellular motility
Enhances cell-to-cell communication and substance exchange
Accelerates tissue repair mechanisms across multiple organ systems
Research applications in wound healing, injury recovery, and regenerative medicine

💪 Muscle & Connective Tissue Research:

Significant increases in muscle growth, endurance, and strength
Reduces muscle spasm and improves overall muscle tone
Prevents formation of adhesions and fibrous bands in muscles, tendons, and ligaments
Stretches connective tissue and maintains flexibility
Research applications in sports medicine, muscle injury, and performance enhancement

🦴 Joint & Anti-Inflammatory Research:

Decreases inflammation in joint tissues
Promotes collagen deposition for structural integrity
Reduces inflammatory cytokines at injury sites
Enhances synovial fluid production and joint lubrication
Research applications in arthritis, joint injury, and inflammatory conditions

🔬 Regenerative Medicine Applications:

Tissue engineering and scaffold development
Stem cell migration and differentiation studies
Organ preservation and transplantation research
Chronic wound healing investigations
Age-related tissue degeneration research

🧪 Cellular & Molecular Research:

Actin-binding protein function studies
Cell cycle regulation and apoptosis research
Growth factor interactions and signaling pathways
Extracellular matrix remodeling investigations
Therapeutic protein development research

Published Research Evidence:

Enhanced wound healing rates in multiple tissue types
Significant improvements in muscle growth and performance metrics
Reduced inflammation markers in joint and muscle tissues
Accelerated angiogenesis and vascular development
Improved tissue flexibility and reduced adhesion formation

Product Specifications:

Purity: ≥99% (HPLC/MS verified)
Molecular Formula: C212H350N56O78S
Molecular Weight: 4963.4 g/mol
Sequence: 43 amino acids (complete thymosin beta-4 sequence)
Format: Lyophilized white powder
Storage: -20°C (long term), 2-8°C (short term)
Stability: 36 months when stored properly
Reconstitution: Sterile water or bacteriostatic water
pH Range: 6.0-8.0 after reconstitution
Solubility: Water soluble