TB-500 (Thymosin Beta-4) is a naturally occurring 43-amino acid peptide that plays a crucial role in cellular repair, regeneration, and protection. This research-grade synthetic version of thymosin beta-4 is identical to the endogenous peptide found in high concentrations in blood platelets, wound fluid, and various tissues throughout the body. TB-500 has gained significant attention in regenerative medicine research for its remarkable ability to promote tissue healing, angiogenesis, and cellular migration.

Research Applications & Scientific Mechanisms:

🩸 Vascular & Angiogenesis Research:

• Promotes endothelial cell differentiation and blood vessel formation

• Enhances angiogenesis in dermal tissues and wound sites

• Stimulates growth of new blood vessels from pre-existing vasculature

• Improves vascular density and circulation in damaged tissues

• Research applications in cardiovascular disease and tissue perfusion studies

🧬 Cellular Migration & Tissue Repair:

• Facilitates keratinocyte migration for wound healing

• Promotes actin polymerization and cellular motility

• Enhances cell-to-cell communication and substance exchange

• Accelerates tissue repair mechanisms across multiple organ systems

• Research applications in wound healing, injury recovery, and regenerative medicine

💪 Muscle & Connective Tissue Research:

• Significant increases in muscle growth, endurance, and strength

• Reduces muscle spasm and improves overall muscle tone

• Prevents formation of adhesions and fibrous bands in muscles, tendons, and ligaments

• Stretches connective tissue and maintains flexibility

• Research applications in sports medicine, muscle injury, and performance enhancement

🦴 Joint & Anti-Inflammatory Research:

• Decreases inflammation in joint tissues

• Promotes collagen deposition for structural integrity

• Reduces inflammatory cytokines at injury sites

• Enhances synovial fluid production and joint lubrication

• Research applications in arthritis, joint injury, and inflammatory conditions

🔬 Regenerative Medicine Applications:

• Tissue engineering and scaffold development

• Stem cell migration and differentiation studies

• Organ preservation and transplantation research

• Chronic wound healing investigations

• Age-related tissue degeneration research

🧪 Cellular & Molecular Research:

• Actin-binding protein function studies

• Cell cycle regulation and apoptosis research

• Growth factor interactions and signaling pathways

• Extracellular matrix remodeling investigations

• Therapeutic protein development research

Published Research Evidence:

• Enhanced wound healing rates in multiple tissue types

• Significant improvements in muscle growth and performance metrics

• Reduced inflammation markers in joint and muscle tissues

• Accelerated angiogenesis and vascular development

• Improved tissue flexibility and reduced adhesion formation

Product Specifications:

• Purity: ≥99% (HPLC/MS verified)

• Molecular Formula: C212H350N56O78S

• Molecular Weight: 4963.4 g/mol

• Sequence: 43 amino acids (complete thymosin beta-4 sequence)

• Format: Lyophilized white powder

• Storage: -20°C (long term), 2-8°C (short term)

• Stability: 36 months when stored properly

• Reconstitution: Sterile water or bacteriostatic water

• pH Range: 6.0-8.0 after reconstitution

• Solubility: Water soluble