Selank is a synthetic heptapeptide derived from tuftsin, originally developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. This research-grade nootropic peptide is extensively studied for its unique mechanisms involving GABA neurotransmitter systems, anxiolytic properties, and cognitive enhancement pathways.

Research Applications & Scientific Interest:

🧠 GABA System Modulation:

Affects 52 genes related to GABA signaling pathways
Modulates GABA receptor affinity without habit-forming properties
Similar anxiolytic effects to benzodiazepines without withdrawal symptoms
Potential synergistic effects with other GABA receptor agonists

🔬 Cognitive & Memory Research:

Enhances memory trace stability and storage processes
Affects 36 genes in hippocampus related to learning and memory
Modulates plasma membrane proteins involved in ion-dependent cognitive processes
Potential neuroprotective effects following brain injury

🩺 Immune System & Inflammation Studies:

Regulates expression of 34 genes involved in inflammatory processes
Selectively suppresses IL-6 production in depression models
Modulates BcI6 gene expression affecting immune system development
Research applications in anxiety-asthenic disorder studies

💊 Enkephalin System Research:

Inhibits enkephalinase activity, protecting natural anxiolytic peptides
Potential pain research applications through opioid receptor pathways
Stress response modulation studies
Natural pain relief mechanism investigations

Published Research Highlights:

Demonstrated anxiolytic effects comparable to classical treatments
Memory enhancement independent of anxiety reduction
Selective immune modulation in specific conditions
Neuroprotective properties in neurotoxicity models

Product Specifications:

Purity: ≥99% (HPLC/MS verified)
Molecular Formula: C33H57N11O9S
Molecular Weight: 751.9 g/mol
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
Format: Lyophilized white powder
Storage: 2-8°C (short term), -20°C (long term)
Stability: 24 months when stored properly
Reconstitution: Sterile water or bacteriostatic water
pH Range: 6.0-8.0 after reconstitution