
Epitalon (also spelled Epithalon) is a synthetic tetrapeptide consisting of four amino acids (Ala-Glu-Asp-Gly) that mimics the activity of epithalamin, a natural hormone produced by the pineal gland. Developed by Professor Vladimir Khavinson in Russia and studied for over 40 years since the 1980s, Epitalon is one of the few compounds shown in research to actually increase telomere length in human cells—a finding with profound implications for understanding cellular aging and longevity.
Telomeres are protective caps on the ends of chromosomes that shorten with each cell division, and when they become too short, cells can no longer divide and become senescent or die, representing a fundamental mechanism of aging. Epitalon works by activating telomerase, the enzyme that rebuilds telomeres, potentially extending cellular lifespan and supporting cellular regeneration capacity.
Human clinical research has demonstrated telomere lengthening in blood cells across different age groups (60-65 and 75-80 age ranges), with benefits comparable to natural epithalamin effects. Animal studies have shown impressive longevity results including increased lifespan in multiple species, improved quality of life in aged animals, reduced incidence of age-related conditions, and decreased spontaneous tumor formation. Long-term studies in elderly populations demonstrated improved cardiovascular function, better lipid profiles, enhanced immune system markers, reduced mortality rates over study periods, and improved biomarkers of aging. Beyond telomerase activation, Epitalon also regulates pineal gland function influencing melatonin production and circadian rhythms, sleep quality, and hormonal balance, while providing antioxidant effects that reduce oxidative stress and protect against free radical damage.
Research protocols typically use intensive cycles of 10-20 days of daily administration, repeated 2-4 times per year, with dose ranges varying from 5-20mg per cycle administered subcutaneously or intramuscularly. Decades of research indicate Epitalon is generally well-tolerated with minimal side effects, good safety profile at research doses, no significant adverse events reported, and good tolerance in elderly populations. Importantly, despite theoretical concerns about telomerase and cancer (since cancer cells use telomerase for immortality), research has shown Epitalon demonstrates tumor-suppressive effects in animal studies with no increased cancer risk observed in long-term studies.
At Vitality Labz, our Epitalon 50mg meets stringent quality standards with 99%+ purity third-party verified, proper tetrapeptide sequence synthesis, complete analytical testing, and Certificate of Analysis provided, though it's important to note this compound has not been FDA-approved and is intended for laboratory research purposes only.
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