Women's Guide to Peptide Therapy: Hormones, Skin, and Vitality

Andrew Davenport, Co-Founder, Vitality Labz•Women's Health

Published February 2025

Throughout my decade of researching human optimization, I've worked with thousands of women seeking to enhance their health, vitality, and longevity. Women face unique physiological challenges—from hormonal fluctuations to skin aging, from pregnancy recovery to menopause transitions. Today, I want to explore how peptides may support women's specific health and wellness goals.

Understanding Women's Unique Physiology

Women's bodies undergo significant changes throughout their lives, influenced by complex hormonal systems that affect everything from energy levels to tissue repair. Key considerations include:

• Hormonal Fluctuations: Monthly cycles, pregnancy, and menopause

• Collagen Changes: Accelerated skin aging after age 30

• Bone Health: Increased osteoporosis risk post-menopause

• Metabolic Shifts: Changes in metabolism and body composition

• Recovery Patterns: Different healing and recovery needs

Important: Women should always consult with healthcare providers familiar with women's health before beginning any peptide regimen, especially during pregnancy, breastfeeding, or menopause transitions.

Hormonal Balance and Peptide Support

Understanding Hormonal Complexity

Women's hormonal systems are intricate networks involving estrogen, progesterone, testosterone, thyroid hormones, and growth factors. Peptides may support these systems indirectly by:

• Supporting cellular repair mechanisms affected by hormonal changes

• May help maintain tissue health during hormonal transitions

• Research suggests potential support for stress response systems

• Possible benefits for sleep quality, which affects hormonal balance

NAD+ and Women's Cellular Health

NAD+ for Energy and Metabolic Support

Research suggests NAD+ may support cellular energy production and metabolic function—areas that many women find challenging, especially during hormonal transitions.

Potential benefits for women may include:

• Support for stable energy levels throughout the day

• May help with metabolic efficiency

• Research indicates potential support for cognitive function

• Possible benefits for sleep quality and circadian rhythms

Epitalon and Women's Longevity

Women often prioritize longevity and healthy aging. Research on Epitalon suggests it may:

• Support cellular aging processes

• May help maintain healthy sleep-wake cycles

• Research indicates potential benefits for stress adaptation

• Possible support for overall vitality as women age

Skin Health and Beauty Applications

The Science of Skin Aging in Women

Women experience accelerated skin aging due to:

• Declining estrogen levels affecting collagen production

• Hormonal fluctuations causing skin changes

• Environmental stressors and UV damage

• Lifestyle factors affecting skin health

BPC-157 for Skin and Tissue Health

Comprehensive Tissue Support

BPC-157 research suggests it may support various tissue repair processes, including those that affect skin health and appearance.

Research indicates BPC-157 may support:

• Natural collagen synthesis processes

• Tissue repair and regeneration

• Healthy inflammatory responses in skin

• Blood flow to skin tissues

TB-500 for Skin Elasticity and Healing

TB-500 research suggests potential benefits for:

• Skin elasticity and flexibility

• Healing of minor skin damage

• Support for healthy skin cell migration

• Possible anti-inflammatory effects on skin

Life Stage-Specific Protocols

Reproductive Years (20s-40s)

During reproductive years, women may focus on:

Focus: Energy, Recovery, and Skin Health

Young women often prioritize sustained energy, exercise recovery, and maintaining healthy skin.

Suggested Considerations:

• • NAD+ for energy and metabolic support

• • BPC-157 for tissue health and minor injury recovery

• • Conservative protocols with regular assessment

Special Considerations

• Pregnancy and Breastfeeding: Peptides should be avoided during these periods

• Menstrual Cycle: Some women adjust timing based on their cycles

• Athletic Performance: Focus on recovery and injury prevention

Perimenopause and Menopause (40s-60s)

This life stage brings significant changes that peptides may help address:

Focus: Hormonal Support and Tissue Maintenance

During hormonal transitions, comprehensive support becomes increasingly important.

Comprehensive Protocol Considerations:

• • NAD+ for energy and metabolic support during hormonal changes

• • BPC-157 for tissue maintenance and joint health

• • TB-500 for skin elasticity and healing support

• • Epitalon for longevity and circadian rhythm support

Addressing Common Concerns

• Hot Flashes: NAD+ may support cellular energy during temperature regulation challenges

• Sleep Disruption: Epitalon research suggests potential circadian rhythm support

• Joint Issues: BPC-157 may support joint and connective tissue health

• Skin Changes: Combined protocols may support overall skin health

Post-Menopause (60+)

Focus shifts to longevity, bone health, and maintaining vitality:

Focus: Longevity and Vitality Maintenance

Post-menopausal women may benefit from comprehensive protocols supporting healthy aging.

Longevity-Focused Protocol:

• • Epitalon for cellular aging support

• • NAD+ for sustained energy and cognitive support

• • BPC-157 for ongoing tissue maintenance

• • TB-500 for mobility and flexibility support

Aesthetic and Cosmetic Applications

Internal Beauty Support

Peptides may support beauty from the inside out by:

• Supporting natural collagen production processes

• May help maintain skin elasticity and firmness

• Research suggests potential benefits for skin healing

• Possible support for healthy hair and nail growth

Combining with Topical Treatments

Many women combine peptide protocols with:

• Quality skincare routines

• Professional aesthetic treatments

• Sun protection and anti-aging practices

• Nutritional support for skin health

Exercise and Recovery for Women

Women's Recovery Patterns

Research suggests women may have different recovery needs:

• Hormonal cycles affect recovery capacity

• Different inflammatory responses to exercise

• Varied protein synthesis patterns

• Unique joint and connective tissue considerations

Exercise-Specific Protocols

Strength Training

• BPC-157 for joint protection and tissue support

• TB-500 for muscle recovery and flexibility

• NAD+ for sustained energy during workouts

Cardio and Endurance

• NAD+ for cellular energy and endurance support

• BPC-157 for cardiovascular tissue health

• Recovery protocols for sustained training

Yoga and Flexibility

• TB-500 for enhanced flexibility and joint mobility

• BPC-157 for connective tissue health

• Focus on injury prevention and tissue maintenance

Dosing and Safety Considerations for Women

General Guidelines

• Start with conservative doses and adjust based on response

• Consider body weight and metabolism differences

• Monitor for any hormonal interactions

• Track menstrual cycle changes if applicable

Timing Considerations

• Morning: NAD+ for energy support

• Pre-Workout: BPC-157 for tissue protection

• Post-Workout: TB-500 for recovery initiation

• Evening: Epitalon for circadian rhythm support

Monitoring and Adjustments

Women should pay special attention to:

• • Changes in menstrual cycle regularity

• • Sleep pattern disruptions

• • Energy level fluctuations

• • Skin or hair changes

• • Any unexpected side effects

Lifestyle Integration

Nutrition Synergy

Peptides work best when combined with proper nutrition:

• Adequate protein for amino acid building blocks

• Antioxidants for cellular protection

• Healthy fats for hormone production

• Micronutrients for optimal peptide function

Stress Management

Chronic stress can impact peptide effectiveness:

• Regular stress reduction practices

• Adequate sleep for optimal peptide function

• Mindfulness and relaxation techniques

• Work-life balance considerations

Working with Healthcare Providers

Finding Knowledgeable Practitioners

• Seek providers familiar with women's health and peptides

• Consider functional medicine practitioners

• Work with providers who understand hormonal complexities

• Ensure regular monitoring and communication

Hormone Testing Considerations

• Baseline hormone panels before starting

• Regular monitoring during protocols

• Adjustments based on hormonal changes

• Integration with other hormone therapies if applicable

Women's health is complex and multifaceted, requiring thoughtful, individualized approaches to peptide therapy. The key is understanding how peptides may support women's unique physiological needs while working closely with knowledgeable healthcare providers. Whether your goals are hormonal balance, skin health, athletic performance, or healthy aging, peptides may offer valuable support when used appropriately and safely.

Andrew Davenport is the co-founder of Vitality Labz Peptides and has spent over a decade researching human optimization and longevity.

Connect with Andrew: [email protected]

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with a healthcare professional before beginning any new supplement regimen.